Amino acid pairing-based self assembling peptides and methods

C - Chemistry – Metallurgy – 07 – K

Patent

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C07K 7/06 (2006.01) A61K 38/02 (2006.01) A61K 45/08 (2006.01) A61K 47/18 (2006.01) A61K 47/42 (2006.01) B82B 1/00 (2006.01) C07K 1/00 (2006.01) C07K 5/06 (2006.01) C07K 5/072 (2006.01) C07K 5/113 (2006.01) C11D 1/88 (2006.01) G01N 33/50 (2006.01) G01N 33/569 (2006.01) G01N 33/66 (2006.01) G01N 33/68 (2006.01) H01M 8/22 (2006.01)

Patent

CA 2697951

The invention relates to self assembling .beta.-strand peptides for forming nanostructures, compositions containing the peptides, and methods of forming the peptides. The invention further relates to uses of these peptides in drug delivery and enhancement of drug solubility, biomolecule detection, and biocatalysis applications. The peptides of this invention are further useful in models of protein aggregation disease.

L'invention porte sur l'auto-assemblage de peptides de brin ß pour former des nanostructures, sur des compositions contenant ces peptides et sur des procédés de formation de ces peptides. L'invention porte en outre sur des utilisations de ces peptides dans l'administration de médicament et l'amélioration de la solubilité de médicament, la détection de biomolécules et des applications de biocatalyse. Les peptides de cette invention sont en outre utiles dans des modèles de maladie dues à l'agrégation de protéines.

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