C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 501/22 (2006.01) A61K 31/4422 (2006.01) A61K 31/472 (2006.01) A61K 31/546 (2006.01) A61K 31/573 (2006.01) C07D 207/34 (2006.01) C07D 211/80 (2006.01) C07D 217/26 (2006.01) C07D 239/10 (2006.01) C07D 257/04 (2006.01) C07D 333/70 (2006.01) C07D 403/10 (2006.01) C07D 471/04 (2006.01) C07D 498/14 (2006.01) C07J 5/00 (2006.01)
Patent
CA 2534342
The present invention is directed to a prodrug comprised of an amino acid bonded to a medicament or drug having a hydroxy, amino, carboxy or acylating derivative thereon. The prodrug has the same utility as the drug from which it is made, but it has enhanced therapeutic properties. In fact, the prodrugs of the present invention enhance at least two therapeutic qualities, as defined herein. The present invention is also directed to pharmaceutical compositions containing same.
La présente invention a trait à un prodrogue comportant un acide aminé lié à un médicament ou drogue portant un groupe hydroxy, amino, carboxy ou dérivé d'acylation. Le prodrogue présente la même utilité que le médicament à partir duquel il est fabriqué, mais présente des propriétés thérapeutiques améliorées. En fait, les prodrogues de la présente invention améliorent au moins deux qualités thérapeutiques, telles que définies dans la description. La présente invention a également trait à des compositions pharmaceutiques contenant un tel prodrogue.
Borden Ladner Gervais Llp
Signature R&d Holdings Llc
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