C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/24 (2006.01) A61K 38/04 (2006.01) A61K 38/16 (2006.01) A61K 39/395 (2006.01) A61P 37/00 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) C07K 14/00 (2006.01) C12N 15/11 (2006.01) C12N 15/13 (2006.01) C07K 14/52 (2006.01)
Patent
CA 2672944
The present invention relates to amino acid sequences that are directed against chemokines, as well as to compounds or constructs, and in particular proteins and polypeptides, that comprise or essentially consist of one or more such amino acid sequences. The invention also relates to nucleic acids encoding such amino acid sequences and polypeptides; to methods for preparing such amino acid sequences and polypeptides; to host cells expressing or capable of expressing such amino acid sequences or polypeptides; to compositions, and in particular to pharmaceutical compositions, that comprise such amino acid sequences, polypeptides, nucleic acids and/or host cells; and to uses of such amino acid sequences or polypeptides, nucleic acids, host ceils and/or compositions, in particular for prophylactic, therapeutic or diagnostic purposes.
La présente invention porte sur des séquences d'acides aminés qui sont dirigées contre des chimiokines, ainsi que sur des composés ou produits de construction, et en particulier sur des protéines et des polypeptides, qui comprennent ou consistent essentiellement en une ou plusieurs telles séquences d'acides aminés. L'invention porte également sur des acides nucléiques codant pour de telles séquences d'acides aminés et polypeptides; sur des procédés pour préparer de telles séquences d'acides aminés et polypeptides; sur des cellules hôtes exprimant ou capables d'exprimer de telles séquences d'acides aminés ou polypeptides; sur des compositions, et, en particulier, sur des compositions pharmaceutiques, qui comprennent de telles séquences d'acides aminés, polypeptides, acides nucléiques et/ou cellules hôtes; et sur les utilisations de telles séquences d'acides aminés ou polypeptides, acides nucléiques, cellules hôtes et/ou compositions, en particulier pour des objectifs prophylactiques, thérapeutiques ou de diagnostic.
Blanchetot Christophe
de Haard Johannes Joseph Wilhelmus
Saunders Michael John Scott
Ablynx N.v.
Fetherstonhaugh & Co.
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