C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/28 (2006.01) A61K 39/395 (2006.01) A61P 35/00 (2006.01) A61P 37/00 (2006.01) C12N 15/13 (2006.01) G01N 33/563 (2006.01)
Patent
CA 2687633
The present invention relates to amino acid sequences that are directed against receptors for growth factors, compounds comprising such sequences, as well as nucleic acid sequences encoding the same. In one embodiment the invention relates to amino acid sequences that bind to a receptor tyrosine kinase. The receptor tyrosine kinase and/or growth factor receptor may be of human origin.In one embodiment the amino acid sequences are NanobodiesTM.
L'invention concerne des séquences d'acides aminés qui sont dirigées contre les récepteurs des facteurs de croissance, des composés renfermant lesdites séquences, et des séquences nucléotidiques codant ces dernières. Dans un mode de réalisation, l'invention se rapporte à des séquences d'acides aminés qui lient un récepteur tyrosine kinase. Le récepteur tyrosine kinase et/ou le récepteur du facteur de croissance peuvent être d'origine humaine. Dans un mode de réalisation, les séquences d'acides aminés sont des nanocorps " NanobodiesTM".
de Haard Johannes Joseph Wilhelmus
Dolk Edward
Gonzalez Pajuelo Maria
Saunders Michael John Scott
Steffensen Soren
Ablynx N.v.
Fetherstonhaugh & Co.
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