C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/22 (2006.01) A61P 19/10 (2006.01)
Patent
CA 2687903
The present invention relates to amino acid sequences that are directed against RANK-L, as well as to compounds or constructs, and in particular proteins and polypeptides, that comprise or essentially consist of one or more such amino acid sequences. The invention also relates to nucleic acids encoding such amino acid sequences and polypeptides; to methods for preparing such amino acid sequences and polypeptides; to host cells expressing or capable of expressing such amino acid sequences or polypeptides; to compositions, and in particular to pharmaceutical compositions, that comprise such amino acid sequences, polypeptides, nucleic acids and/or host cells; and to uses of such amino acid sequences or polypeptides, nucleic acids, host cells and/or compositions, in particular for prophylactic, therapeutic or diagnostic purposes.
L'invention se rapporte à des séquences d'acides aminés qui sont dirigées contre RANK-L, et à des composés ou des produits de recombinaison, et en particulier des protéines et des polypeptides, qui comprennent une ou plusieurs desdites séquences d'acides aminés ou qui sont essentiellement composés d'une ou plusieurs desdites séquences d'acides aminés. L'invention porte également sur des acides nucléiques codant lesdites séquences d'acides aminés et polypeptides; sur des procédés de préparation desdites séquences d'acides aminés et polypeptides; sur des cellules hôtes exprimant ou capables d'exprimer lesdites séquences d'acides aminés ou polypeptides; sur des compositions, et en particulier des compositions pharmaceutiques, qui renferment lesdites séquences d'acides aminés, polypeptides, acides nucléiques et/ou cellules hôtes; et sur des utilisations desdites séquences d'acides aminés ou polypeptides, acides nucléiques, cellules hôtes et/ou compositions, en particulier à des fins prophylactiques, thérapeutiques ou diagnostiques.
Beirnaert Els
Cornelis Sigrid
Hoogenboom Hendricus Renerus Jacobus Matteus
Ablynx N.v.
Fetherstonhaugh & Co.
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