C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/22 (2006.01)
Patent
CA 2678218
The present invention relates to amino acid sequences that are directed against vascular endothelial growth factor (VEGF), as well as to compounds or constructs, and in particular proteins and polypeptides, that comprise or essentially consist of one or more such amino acid sequences. The amino acid sequences, compounds and constructs can be used for prophylactic, therapeutic or diagnostic purposes, such as for the treatment of conditions and diseases characterized by excessive and/or pathological angiogenesis or neovascularization.
La présente invention concerne des séquences d'acides aminés dirigées contre le facteur de croissance de l'endothélium vasculaire (VEGF), ainsi que des composés ou des gènes hybrides et, en particulier, des protéines et des polypeptides, comprenant une ou plusieurs de ces séquences d'acides aminés ou essentiellement constitués d'une ou plusieurs de ces séquences d'acides aminés. Ces séquences d'acides aminés, ces composés et ces gènes hybrides peuvent être utilisés à des fins préventives, thérapeutiques ou diagnostiques, telles que pour le traitement de troubles et de maladies se caractérisant par une angiogenèse ou une néovascularisation excessive et/ou pathologique.
Hoogenboom Hendricus Renerus Jacobus Mattheus
Merchiers Pascal Gerard
Verheesen Peter
Ablynx N.v.
Fetherstonhaugh & Co.
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