Amino acid sequences that bind to a desired molecule in a...

C - Chemistry – Metallurgy – 07 – K

Patent

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C07K 16/18 (2006.01)

Patent

CA 2664903

The present invention relates to amino acid sequences that bind to serum proteins such as serum albumin; to compounds, proteins and polypeptides comprising or essentially consisting of such amino acid sequences; to nucleic acids that encode such amino acid sequences, proteins or polypeptides; to compositions, and in particular pharmaceutical compositions, that comprise such amino acid sequences, proteins and polypeptides; and to uses of such amino acid sequences, proteins and polypeptides, is essentially conditional on different physiological situations, e.g. is different under acidic condition than under pH-neutral condition.

La présente invention concerne des séquences d'acides aminés se liant à des protéines sériques telles que l'albumine sérique; des composés, protéines et polypeptides comprenant de telles séquences d'acides aminés ou essentiellement constitués de celles-ci; des acides nucléiques qui codent de tels polypeptides, séquences d'acides aminés ou protéines; des compositions et en particulier des compositions pharmaceutiques comprenant de tels polypeptides, séquences d'acides aminés, ou protéines; et les utilisations de tels polypeptides, séquences d'acides aminés, ou protéines, de façon essentiellement conditionnelle en fonction de différentes situations physiologiques, par exemple avec des différences sous conditions acides par rapport aux conditions de pH-neutre.

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