Amino acid substituted molecules

Details Amino acid substituted molecules Amino acid substituted molecules

C - Chemistry, Metallurgy

07

K

C07K 1/00 (2006.01) A61K 38/00 (2006.01) C07K 1/107 (2006.01) C07K 1/113 (2006.01) C07K 14/565 (2006.01) C12P 21/02 (2006.01)

Patent

CA 2707840

The invention provides compositions and methods of identifying, modifying and producing modified target molecules, including therapeutic molecules by modification with non-natural amino acids. Certain aspects of the invention include methods of adding a chemical moiety to a target molecule, and the compositions resulting therefrom. Certain aspects of the invention also relate to kits for identifying, modifying and producing modified target molecules described herein.

Cette invention a trait à des compositions et à des procédés permettant d'identifier, de modifier et de produire des molécules cibles modifiées, y compris des molécules thérapeutiques par modification avec des acides aminés non naturels. Certains aspects de l'invention comprennent des procédés d'addition d'une fraction chimique à une molécule cible, et aux compositions résultantes. Certains aspects de l'invention concernent également des kits permettant d'identifier, de modifier et de produire les molécules cibles modifiées décrites ici.

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