Amino acid substituted molecules

Details Amino acid substituted molecules Amino acid substituted molecules

C - Chemistry, Metallurgy

12

P

C12P 21/02 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01)

Patent

CA 2653748

The invention provides compositions and methods of identifying, modifying and producing modified target molecules, including therapeutic molecules by modification with non-natural amino acids. Certain aspects of the invention include methods of adding a chemical moiety to a target molecule, and the compositions resulting therefrom. Certain aspects of the invention also relate to kits for identifying, modifying and producing modified target molecules described herein.

L'invention concerne des compositions et des procédés d'identification, de modification et de production de molécules cibles modifiées, notamment de molécules thérapeutiques par modification avec des acides aminés non naturels. Certains aspects de l'invention concernent des procédés consistant à ajouter une entité chimique à une molécule cible, ainsi que les compositions obtenues par ces procédés. Certains aspects de l'invention concernent également des trousses pour identifier, modifier et produire lesdites molécules cibles modifiées.

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