Amino acids from fish and soy proteins improve insulin...

A - Human Necessities – 61 – K

Patent

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A61K 38/01 (2006.01) A23K 1/10 (2006.01) A23K 1/16 (2006.01) A23L 1/305 (2006.01) A61K 31/195 (2006.01) A61K 38/16 (2006.01) A61K 38/17 (2006.01) A61P 3/10 (2006.01)

Patent

CA 2376197

The present invention describes the use of fish protein (namely cod protein) and soy protein to improve the peripheral insulin resistance in a human or non- human animal. Fish and soy protein were administered to rats submitted to high- sucrose or high-fat/sucrose diets, which are animal models for diabetes. It was found that fish and soy protein efficiently control glucose utilization, and that fish protein is particularly effective in muscle tissue. This effect is not observed when rats are given casein. Fish and soy protein are therefore promising for controlling insulin-resistance, diabetes and complications resulting therefrom, such as obesity.

L'invention concerne décrit l'utilisation de protéines de poisson (plus précisément, de morue) et de soja pour améliorer la résistance périphérique à l'insuline chez les humains et les animaux. Ces protéines de poisson et de soja ont été administrées à des rats, qui sont des animaux modèles pour le diabète, soumis à des diètes à forte teneur en saccharose ou à forte teneur en matières grasses et en saccharose. On a découvert que les protéines de poisson et de soja régulent efficacement l'utilisation de glucose et que les protéines de poisson sont particulièrement efficaces sur les tissus musculaires. Cet effet n'est pas observé lorsqu'on administre de la caséine aux rats. Les protéines de poisson et de soja sont donc susceptibles d'être efficaces pour la régulation de la résistance à l'insuline, du diabète et de complications en résultant, telle que l'obésité.

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