Amino acids in micelle preparation

Details Amino acids in micelle preparation Amino acids in micelle preparation

A - Human Necessities

61

K

A61K 31/337 (2006.01) A61K 9/10 (2006.01) A61K 9/107 (2006.01) A61K 47/18 (2006.01) A61K 47/30 (2006.01)

Patent

CA 2454629

Formulations are formed of a diblock copolymer (X-Y) having a hydrophilic block X comprising residues of monomer x, and a hydrophobic block Y comprising residues of monomer y; an additive selected from an amino acid and an oligopeptide. Upon admixture with water, the formulations form drug delivery vehicles, preferably in micellar form. The inclusion of amino acid and/or oligopeptide provides for the formation of micelles at an enhanced rate, and/or provides the formation of micelles having an enhanced ability to incorporate drug(s), and/or provides the formation of micelles having advantageous physical characteristics.

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