Amino alcohol compound

A - Human Necessities – 61 – K

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A61K 31/40 (2006.01) A61P 7/00 (2006.01) A61P 37/06 (2006.01)

Patent

CA 2557536

A medicinal composition effective in reducing the number of peripheral-blood lymphocytes. It is less toxic and is excellent in physical properties and internal behavior. The medicinal composition contains a compound having the general formula (I): [Chemical formula 1] (I) (wherein R1 represents methyl or ethyl; R2 represents methyl or ethyl; and R3 represents phenyl substituted by one to three substituents selected from the group consisting of halogeno, lower alkyl, cycloalkyl, lower alkoxy, halogenated lower alkyl, lower aliphatic acyl, and cyano), or a pharmacologically acceptable salt or ester of the compound.

Une composition médicinale efficace pour réduire le nombre de lymphocytes sanguins périphériques. Elle est moins toxique et est excellente en termes de propriétés physiques et de comportement interne. La composition médicinale contient un composé ayant la formule générale (I) : [Formule chimique 1] (I) (dans laquelle R?1¿ représente un groupe méthyle ou éthyle ; R?2¿ représente un groupe méthyle ou éthyle ; et R?3¿ représente un groupe phényle substitué par un à trois substituants choisis dans le groupe comprenant l~halogéno, l~alkyle inférieur, le cycloalkyle, l~alcoxy inférieur, l~alkyle halogéné inférieur, l~acyle aliphatique inférieur, et le cyano), ou un sel ou un ester pharmacologiquement acceptables du composé.

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