Amino-aza-adamantane derivatives and methods of use

Details Amino-aza-adamantane derivatives and methods of use Amino-aza-adamantane derivatives and methods of use

C - Chemistry, Metallurgy

07

D

C07D 471/18 (2006.01) A61K 31/435 (2006.01) A61P 25/00 (2006.01) C07D 487/04 (2006.01) C07D 487/08 (2006.01)

Patent

CA 2622701

The invention relates to amine-substituted aza-adamantane derivatives, compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and compositions. Radiolabelled compounds useful for evaluating the binding affinity to .alpha.7 nicotinic acetylcholine receptors also are described.

L'invention concerne des dérivés d'aza-adamantane à substitution amine, des compositions comprenant lesdits composés, ainsi que des méthodes de traitement d'affections et de troubles à l'aide desdits composés et desdites compositions. L'invention concerne également des composés radiomarqués utiles pour évaluer l'affinité de liaison à des récepteurs de l'acétylcholine nicotinique .alpha.7.

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