Amino-heterocyclic compounds

Details Amino-heterocyclic compounds Amino-heterocyclic compounds

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01)

Patent

CA 2687035

The invention provides PDE9-inhibiting compounds of Formula (I), and pharmaceutically acceptable salts thereof, wherein R, R1, R2 and R3 are as defined herein. Pharmaceutical compositions containing the compounds of Formula I, and uses thereof in treating neurodegenerative and cognitive disorders, such as Alzheimer's disease and schizophrenia, are also provided.

L'invention porte sur des composés inhibant PDE9 de Formule (I) et sur des sels pharmaceutiquement acceptables de ceux-ci, où R, R1, R2 et R3 sont tels que définis présentement. L'invention porte également sur des compositions pharmaceutiques contenant les composés de Formule I et sur les utilisations de celles-ci dans le traitement de troubles neurodégénératifs et cognitifs, tels que la maladie d'Alzheimer et la schizophrénie.

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