Amino-imidazolones for the inhibition of beta-secretase

Details Amino-imidazolones for the inhibition of beta-secretase Amino-imidazolones for the inhibition of beta-secretase

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/519 (2006.01) A61P 25/28 (2006.01)

Patent

CA 2593515

The present invention provides an amino-imidazolone compound of formula I Chemical formula should be inserted here as it appears on the abstract in paper form. Also provided are compositions and methods for the use thereof to inhibit .beta.-secretase (BACE) and treat .beta.-amyloid deposits and neurofibrillary tangles.

La présente invention concerne un composé d'amino-imidazolone de formule (I). Elle concerne également des compositions et des méthodes d'utilisation du composé pour inhiber la ß-sécrétase (BACE) et traiter des dépôts ß-amyloïdes et des enchevêtrement neurofibrilaires.

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