C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 413/12 (2006.01) A61K 31/55 (2006.01) C07D 243/10 (2006.01) C07D 243/24 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 405/12 (2006.01) C07D 407/12 (2006.01) C07D 409/12 (2006.01) C07D 409/14 (2006.01) C07D 417/12 (2006.01)
Patent
CA 2384544
This invention relates to novel lactams having Formula (I), to their pharmaceutical compositions and to their methods of use. These novel compounds inhibit the processing of amyloid precursor protein and, more specifically, inhibit the production of A.beta.-peptide, thereby acting to prevent the formation of neurological deposits of amyloid protein. More particularly, the present invention relates to the treatment of neurological disorders related to .beta.-amyloid production such as Alzheimer's disease and Down's Syndrome.
La présente invention concerne de nouveaux lactames représentés par la formule (I), leurs compositions pharmaceutiques et leurs procédés d'utilisation. Ces nouveaux composés empêchent la transformation de la protéine précurseur amyloïde et, plus spécifiquement empêchent la production de peptide A.beta., ayant ainsi une action préventive sur la formation des dépôts neurologiques de protéine amyloïde. Cette invention se rapporte plus particulièrement au traitement des troubles neurologiques associés à la production d'amyloïde .beta., tels que la maladie d'Alzheimer et le syndrome de Down.
Han Amy Qi
Thompson Lorin Andrew
Bristol-Myers Squibb Pharma Company
Dimock Stratton Llp
Han Amy Qi
Thompson Lorin Andrew
LandOfFree
Amino lactam sulfonamides as inhibitors of a.beta. protein... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Amino lactam sulfonamides as inhibitors of a.beta. protein..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Amino lactam sulfonamides as inhibitors of a.beta. protein... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1475166