Amino nitrile intermediate for the preparation of alanine...

Details Amino nitrile intermediate for the preparation of alanine... Amino nitrile intermediate for the preparation of alanine...

C - Chemistry, Metallurgy

07

C

C07C 255/25 (2006.01) C07C 253/30 (2006.01) C11D 3/33 (2006.01)

Patent

CA 2216229

A novel intermediate useful in the synthesis of alpha-alanine diacetic acid or its salts is disclosed. The intermediate can be formed by contacting alanine with glycolonitrile under alkaline conditions or glycine with lactonitrile to form an aminonitrile which can be hydrolyzed and then contacted with additional glycolonitrile to form the nitrile intermediate which can be converted to alpha-alanine diacetic acid via hydrolysis.

Nouvel intermédiaire utilisé dans la synthèse de l'acide alpha-alanine diacétique ou de ses sels. On obtient cet intermédiaire en mettant l'alanine en contact avec un glycolonitrile dans des conditions alcalines, ou de la glycine avec un lactonitrile pour former un aminonitrile qui peut être hydrolysé puis mis en contact avec une quantité supplémentaire de glycolonitrile pour former l'intermédiaire nitrile. Ce dernier peut alors être converti en acide alpha-alanine diacétique par hydrolyse.

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