C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 403/04 (2006.01) C07C 231/10 (2006.01) C07D 205/085 (2006.01) C07D 403/12 (2006.01) C07D 405/14 (2006.01) C07D 463/00 (2006.01) C07D 501/58 (2006.01) C07F 7/10 (2006.01)
Patent
CA 2041897
X-7852 Abstract A method for preparing a new class of protected amino intermediates is provided which utilizes reaction of an imido protected primary amine with a secondary amine. The intermediates thus provided are suitably protected for nucleophilic functionalization of the residue of the primary amine. The desired imido pro- tected amine thus derivatized may be regenerated using acid. Further provided are methods for resolving racemic primary amines. Also provided are .beta.-lactam intermediates protected with the new amino protecting group which are useful in the preparation of .beta.-lactam antibiotics.
Eli Lilly And Company
Gowling Lafleur Henderson Llp
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