Amino-pyridines as inhibitors of .beta.-secretase

Details Amino-pyridines as inhibitors of .beta.-secretase Amino-pyridines as inhibitors of .beta.-secretase

C - Chemistry, Metallurgy

07

D

C07D 401/06 (2006.01) A61K 31/44 (2006.01) A61K 31/495 (2006.01) A61P 25/00 (2006.01) C07D 401/14 (2006.01) C07D 405/14 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2593857

The present invention provides an amino-pyridine compound of formula (I). The present invention also provides methods for the use thereof to inhibit .beta. - secretase (BACE) and treat .beta. -amyloid deposits and neurofibrillary tangles.

La présente invention concerne une aminopyridine représentée par la formule (I). L'invention concerne également des méthodes d'utilisation de ce composé pour inhiber la .beta.-sécrétase (BACE) et traiter des dépôts .beta.-amyloïdes et une dégénérescence neurofibrillaire.

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