Amino-spiro ¬oxa(or thia) cycloalkane-penam|- carboxylic acids

Details Amino-spiro ¬oxa(or thia) cycloalkane-penam|- carboxylic acids Amino-spiro ¬oxa(or thia) cycloalkane-penam|- carboxylic acids

C - Chemistry, Metallurgy

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C07D 499/42 (2006.01) C07D 305/08 (2006.01) C07D 307/18 (2006.01) C07D 309/08 (2006.01) C07D 309/20 (2006.01) C07D 331/04 (2006.01) C07D 333/34 (2006.01) C07D 335/02 (2006.01) C07D 499/00 (2006.01) C07D 513/10 (2006.01)

Patent

CA 1101411

A B S T R A C T o f t h e D I S C L O S U R E Amino-spiro[oxa(or thia)cycloalkane-penam]-carboxylic acid, a salt or an ester thereof, of the formula (I) Image wherein Z is a hydrogen or a group protecting the carboxylic function, X is a sulfur or oxygen atom, n is 1 or 2, m is 1 or 2, and process of preparing the same. These compounds are useful as intermediates in the synthesis of a new group of antibiotics having properties similar to penicillins, besides own antibiotic activity with a broad antibacterial spectrum.

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