Amino-substituted benzenesulfonylureas and -thioureas,...

C - Chemistry – Metallurgy – 07 – D

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C07D 295/155 (2006.01) A61K 31/17 (2006.01) A61K 31/395 (2006.01) C07C 311/58 (2006.01) C07C 335/42 (2006.01) C07D 295/135 (2006.01)

Patent

CA 2137441

There are described amino-substituted benzenesulfonylureas and -thioureas of the formula I (see formula I) Image The compounds I are used for the treatment of cardiac arrhythmias and for the prevention of sudden heart death caused by arrhythmias and can therefore be used as antiarrhythmics. They are particularly suitable for those cases in which arrhythmias are a result of constriction of a coronary vessel, such as in angina pectoris or in acute cardiac infarct.

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