Amino substituted diaryl[a,d]cycloheptene analogs as...

Details Amino substituted diaryl[a,d]cycloheptene analogs as... Amino substituted diaryl[a,d]cycloheptene analogs as...

C - Chemistry, Metallurgy

07

D

C07D 403/04 (2006.01) A61K 31/445 (2006.01) A61K 31/551 (2006.01) A61P 25/00 (2006.01) A61P 25/28 (2006.01)

Patent

CA 2550735

Disclosed herein are analogs of clozapine and pharmaceutically acceptable salts, esters, amides, or prodrugs thereof; methods of synthesizing the analogs; and methods of using the analogs for treating neuorpsychiatric disorders. In some embodiments, the analogs are amino substituted diaryl[a,d]cycloheptenes.

L'invention concerne des analogues de clozapine, ainsi que des sels, des esters, des amides pharmaceutiquement acceptables ou des promédicaments de ceux-ci. L'invention concerne en outre des procédés d'utilisation de ces analogues pour le traitement de troubles neuropsychiatriques. Dans certaines formes d'exécution, les analogues sont des diaryl[a,d]cycloheptènes amino substitués.

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