Amino-substituted piperidino-derivatives

Details Amino-substituted piperidino-derivatives Amino-substituted piperidino-derivatives

C - Chemistry, Metallurgy

07

D

260/241.1, 260/2

C07D 471/04 (2006.01)

Patent

CA 1049512

Abstract of the Disclosure The invention discloses novel compounds of the general formula: Image in which the keto group is present at position 2 or 3 and in which X stands for oxygen, sulphur, the group Image or the group -CR8R9-; R1, R2, R3 and R4 represent hydrogen, hydroxy, halogen, alkyl (1-6 C), alkoxy (1-6 C), alkylthio (1-6 C) or trifluoromethyl; R7 stands for hydrogen or alkyl (1-4 C) alkylthio R8 and R9 stand for hydrogen or methyl. The compounds are useful as inte- mediates in the production of amino-substituted piperidino-derivatives having valuable central nervous system (CNS) activity, especially antidepressant activity.

288947

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