Amino-sugar derivatives, process for their preparation and...

C - Chemistry – Metallurgy – 07 – H

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C07H 15/22 (2006.01) C07H 17/00 (2006.01) C07H 17/02 (2006.01) C07H 19/02 (2006.01) C07H 19/04 (2006.01)

Patent

CA 1096375

Abstract of the Disclosure The present invention provides amino-sugar derivatives of the general formula Image -X in which n and m independently of each other represent an integer from 0 to 8 and the sum n + m has a value of 0 to 8, and X designates a group -OR, -SH, -SR, -NH2, -NHR or NRH1, in which R designates an alkyl, alkenyl, cycloalkyl, aralkyl, aryl or heterocyclic radical, which can be substituted, and R1 designates an alkyl, cycloalkyl, aralkyl or aryl radical, which can be substituted, or R and R1, together with the nitrogen atom to which they are bonded, form a heterocyclic ring. It has been found that the compounds of the formula (II) are highly active inhibitors for glycoside hydrolases of the digestive tract. Also included in the invent are are methods of preparing the amino-sugar derivatives of the invention, compositions containing said amino-sugar derivatives and methods for the use of said amino-sugar derivatives and compositions containing them. Le A 17 589

293546

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