Amino-thiazole and oxazole derivatives

Details Amino-thiazole and oxazole derivatives Amino-thiazole and oxazole derivatives

C - Chemistry, Metallurgy

07

D

167/231, 260/278

C07D 413/04 (2006.01) C07D 417/04 (2006.01) C07D 417/14 (2006.01)

Patent

CA 1294965

ABSTRACT AMINO-THIAZOLE AND OXAZOLE DERIVATIVES The present invention relates to new amino-thiazole and amino- oxazole derivatives of the general formula: Image I wherein: R represents hydrogen, a lower alkyl group with 1 to 4 carbon atoms, a lower alkenyl group, a phenyl-alkyl (1-4 C), furanyl-alkyl (1-4 C) or thienyl-alkyl (1-4 C) group; X represents sulphur or oxygen; R1 and R2 represent hydrogen or alkyl (1-4 C), and the dotted line represents an optional extra bond, as well as pharmaceutically acceptable acid addition salts thereof, having potent dopamine-agonist activity.

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