Aminoacyl prodrugs as an active pharmaceutical ingredient...

Details Aminoacyl prodrugs as an active pharmaceutical ingredient... Aminoacyl prodrugs as an active pharmaceutical ingredient...

C - Chemistry, Metallurgy

07

D

C07D 413/14 (2006.01) A61K 31/422 (2006.01) A61P 7/02 (2006.01)

Patent

CA 2693507

The present application relates to prodrug derivatives of 5-chloro-N-({(5S)-3- [2-fluoro-4-(3- oxomorpholin-4-yl)phenyl]-2-oxo-1,3-oxazolidin-5-yl}methyl)thiophene-2- carboxamide, processes for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, especially of thromboembolic disorders.

La présente invention concerne des prodrogues dérivés du 5-chloro- N-({(5S)-3-[2-fluoro-4-(3- oxomorpholin-4-yl)phényl]-2-oxo-1,3- oxazolidin-5-yl}méthyl)thiophène-2-carboxamide, des procédés pour les préparer, leur utilisation pour le traitement et/ou la prévention de maladie, ainsi que leur utilisation pour préparer des médicaments destinés au traitement et/ou à la prévention de maladies, en particulier d'affections thromboemboliques.

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