Aminoacyl trna synthetases

Details Aminoacyl trna synthetases Aminoacyl trna synthetases

C - Chemistry, Metallurgy

12

N

C12N 15/52 (2006.01) A61K 38/17 (2006.01) C07K 16/40 (2006.01) C12N 9/00 (2006.01) C12N 15/63 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01) G01N 33/53 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2431493

The invention provides human aminoacyl tRNA synthetases (ATRS) and polynucleotides which identify and encode ATRS. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of ATRS.

L'invention concerne des aminoacyl ARNt synthétases (ATRS) humaines et des polynucléotides qui identifient des ATRS et codent pour ces derniers. L'invention porte également sur des vecteurs d'expression, des cellules hôtes, des anticorps, des agonistes et des antagonistes. De plus, l'invention concerne des méthodes de diagnostic, de traitement et de prévention de troubles associés à une expression aberrante des ATRS.

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