Aminoacyl trna synthetases

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 9/00 (2006.01) A61K 38/53 (2006.01)

Patent

CA 2408315

The invention provides human aminoacyl tRNA synthetases (ATRS) and polynucleotides which identify and encode ATRS. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of ATRS.

L'invention concerne des aminoacyl-ARNt synthétases humaines (ATRS), ainsi que des polynucléotides permettant d'identifier ces ATRS et codant pour ces dernières. L'invention concerne également des vecteurs d'expression, des cellules hôtes, des anticorps, des agonistes, et des antagonistes. L'invention concerne enfin des méthodes de diagnostic, de traitement ou de prévention de troubles associés à une expression aberrante d'ATRS.

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