C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 215/06 (2006.01) A61K 31/138 (2006.01) A61P 1/00 (2006.01) C07C 215/54 (2006.01) C07C 217/30 (2006.01) C07C 217/58 (2006.01) C07C 217/60 (2006.01) C07C 217/62 (2006.01) C07C 217/72 (2006.01) C07C 217/86 (2006.01) C07C 229/34 (2006.01) C07C 229/38 (2006.01) C07C 233/43 (2006.01) C07C 237/08 (2006.01) C07C 271/28 (2006.01) C07C 311/08 (2006.01) C07C 311/28 (2006.01) C07C 317/36 (2006.01) C07C 323/25 (2006.01) C07C 323/32 (2006.01)
Patent
CA 2341458
This invention relates to new aminoalcohol derivatives or salts thereof represented by formula (I) wherein each symbol is as defined in the specification or salts thereof which have .beta.3 adrenergic agonist activity and therefore have gut selective sympathomimetic, anti-ulcerous, anti- pancreatitis, lipolytic, anti-urinary incontinence and anti-pollakiuria activities, to processes for the preparation thereof, to a pharmaceutical composition comprising the same and to a method for the prevention and/or treatment of diseases indicated in the specification to a human being or an animal.
La présente invention concerne de nouveaux dérivés d'aminoalcool et leurs sels, représentés par la formule (I), dans laquelle chaque symbole est tel que défini dans le descriptif. Lesdits dérivés et leurs sels font office d'agonistes du récepteur .beta.3-adrénergique, et ils exercent, de ce fait, une activité sélective pour le tube digestif, sympathomimétique, anti-ulcéreuse, anti-pancréatite, lipolytique, anti-incontinence urinaire et antipollakiurie. L'invention concerne également des procédés de préparation de ces composés, une composition pharmaceutique les contenant, ainsi qu'un procédé de prévention et/ou de traitement des maladies indiquées dans le descriptif chez l'homme ou chez l'animal.
Fujii Naoaki
Sakurai Minoru
Takasugi Hisashi
Taniguchi Kiyoshi
Tomishima Yasuyo
Fujisawa Pharmaceutical Co. Ltd.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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