C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 209/08 (2006.01) A61K 31/404 (2006.01) A61K 31/454 (2006.01) A61P 25/00 (2006.01) C07D 209/30 (2006.01) C07D 401/12 (2006.01)
Patent
CA 2683124
The present invention relates to novel aminoalkoxy arylsulfonamide compounds of the formula (I), their derivatives, their stereoisomers, their pharmaceutically acceptable salts and pharmaceutically acceptable compositions containing them. The present invention also relates to a process for the preparation of above said novel compounds, their derivatives, their stereoisomers, their pharmaceutically acceptable salts and pharmaceutically acceptable compositions containing them. These compounds are useful in the treatment of various disorders that are related to 5-HT6 receptor functions. Specifically, the compounds of this invention are also useful in the treatment of various CNS disorders, hematological disorders, eating disorders, diseases associated with pain, respiratory diseases, genito-urological disorders, cardiovascular diseases and cancer.
La présente invention concerne de nouveaux composés aminoalcoxy arylsulfonamides de la formule (I), leurs dérivés, leurs stéréo-isomères, leurs sels acceptables du point de vue pharmaceutique et des compositions acceptables du point de vue pharmaceutique les contenant. La présente invention concerne également un procédé pour la préparation desdits nouveaux composés ci-dessus, de leurs dérivés, de leurs stéréo-isomères, de leurs sels acceptables du point de vue pharmaceutique et des compositions acceptables du point de vue pharmaceutique les contenant. Ces composés s'utilisent dans le traitement de divers troubles qui sont associés à des fonctions du récepteur 5-HT6. De façon précise, les composés de cette invention s'utilisent également dans le traitement de divers troubles du système nerveux central, hématologiques, de l'alimentation, génito-urologiques, ainsi que dans le traitement de maladies associées à la douleur, de maladies respiratoires, de maladies cardiovasculaires et du cancer.
Daulatabad Anand Vijaykumar
Dwarampudi Adi Reddy
Jasti Venkateswarlu
Kambhampati Rama Sastri
Kandikere Nagaraj Vishwottam
Kirby Eades Gale Baker
Suven Life Sciences Limited
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