Aminoalkyl furan derivatives

Details Aminoalkyl furan derivatives Aminoalkyl furan derivatives

C - Chemistry, Metallurgy

07

D

260/363.3, 260/3

C07D 307/54 (2006.01) C07D 307/52 (2006.01)

Patent

CA 1148556

III. Abstract: Compoundsd of the formula Image I wherein R3 is a straight or branched chain alkynyl group containing from 3 to 9 carbon atoms. inclusive; R2 and R3 are the same or different and are hydrogen, (lower)- alkyl, (lower)alkenyl, (lower)alkynyl or Ar; R4 is hydrogen or (lower)alkyl; n is an integer of from 1 to 6, p is 1 or 2 and q is 2 or 3, provided that the sum of p and q is 3 or 4, x is NR5 or CHR5, R5 is cyano, nitro, SO2Ar or SO2 (lower)alkyl; and Ar is an optionally substituted phenyl group; and nontoxic, pharmaceutically acceptable salts thereof, are potent anti-ulcer agents. Processes for their preparation and novel intermediates are also disclosed.

335562

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