C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
167/208, 260/263
C07D 277/38 (2006.01) A61K 31/395 (2006.01) C07D 277/40 (2006.01) C07D 277/42 (2006.01) C07D 417/06 (2006.01) C07D 417/12 (2006.01) C07D 417/14 (2006.01)
Patent
CA 2020288
- 18 - O.Z. 0050/40949 Abstract of the Disclosure: Aminoalkyl-substituted 2- aminothiazole derivatives of the general formula Image I where R1 and R2, which may be identical or different, are each hydrogen, C1-C5-alkyl, phenyl or C1-C5-alkanoyl, R3 is C1-C5-alkyl, phenyl which is unsubstituted or mono- substituted by halogen, C1-C5-alkyl or C1-C5-alkoxy, or thienyl, n is an integer of from 2 to 6, and NR4R5 is one of the groups a, b, c or d Image , Image , Image , Image , a b c d where Ar is a phenyl ring which is unsubstituted or monosubstituted by C1-C5-alkyl, C1-C5-alkoxy, halogen, hydroxyl, nitro or trifluoromethyl, or is pyridyl, pyrimidinyl or thienyl, R6 is H or C1-C5-alkyl and R7 is phenyl which is unsubstituted or monosubstituted by C1- C5-alkyl, C1-C5 alkoxy, halogen, hydroxyl or trifluoro- methyl, or R7 is thienyl, with the proviso that R3 is C1- C5-alkyl only when either R1 and R2 are not both simul- taneously H or when NR4R5 is the group d, and their salts with physiologically tolerated acids, their preparation, their use for the preparation of a drug, and the drugs.
Rendenbach-Mueller Beatrice
Teschendorf Hans-Juergen
Unger Liliane
Basf Aktiengesellschaft
Robic
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