Aminoalkyl substituted benzo-heterocyclic compounds

Details Aminoalkyl substituted benzo-heterocyclic compounds Aminoalkyl substituted benzo-heterocyclic compounds

C - Chemistry, Metallurgy

07

D

C07D 217/24 (2006.01) A61K 31/33 (2006.01) C07D 215/20 (2006.01) C07D 217/14 (2006.01) C07D 231/56 (2006.01) C07D 237/30 (2006.01) C07D 239/10 (2006.01) C07D 239/74 (2006.01) C07D 239/82 (2006.01) C07D 261/20 (2006.01) C07D 265/02 (2006.01) C07D 275/04 (2006.01) C07D 275/06 (2006.01) C07D 307/79 (2006.01) C07D 311/16 (2006.01) C07D 311/58 (2006.01) C07D 333/54 (2006.01)

Patent

CA 2190708

Aminoalkyl-substituted benzo-heterocyclic compounds of the formula Image wherein R is either a group of the formula Image (R') T is H, alkyl, halogen, N(R2,R21), CONH2, CN, NO2, CF3, OH or alkyl (O or S), R2 and R21 are alkyl or H and Q is cycloalkyl, optionally substituted phenyl or alkyl alkenyl or optionally substituted by OH, or wherein one of R and T is halogen or H and the other is H, alkyl, halogen, N(R2,R21), CONH2, CN, NO2, CF3, OH or alkyl(O or S) and Q is a group of the formula (Q") Image A1 is alkyl or alkenyl and A2 is cycloalkyl, cycloalkyl-alkyl or optionally substituted alkyl or alkenyl or A1 and A2 together are substituted alkylene or alkenylene, L1 is a group L bonded to the benzo group directly or via 0, NH or N(alkyl or alkanoyl), L2 is a group L bonded to the phenyl group via O, NH or N(alkyl or alkanoyl), L is an alkylene alkenylene or cycloalkylene-alkylene, the dotted bond emanating from M is optional, M is a 2- or 3-membered grouping which can contain an O or S atom or a S(O), S(O)2 or C(O) group and/or up to two N atoms or N(R6) groups and/or up to two C(R6) or CH(R6) groups, but contains in total at least one optionally substituted hetero atom and R6 is H or alkyl, and acid addition salts thereof.

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