A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/662 (2006.01) A61K 31/675 (2006.01) A61K 31/685 (2006.01) A61P 19/08 (2006.01)
Patent
CA 2382877
A method for preventing or minimizing loss of bone mineral in mammals which method comprises administering to a mammal an amount of an aminoalkylenephosphonate which is effective to prevent or minimize loss of bone mineral density. The aminoalkylenephosphonates of the present invention should have at least one R-N(Alk-PO3H2)2 group or at least two RRïN-Alk-PO3H2 groups wherein R and Rï can be, same or different, aliphatic or cyclic moiety, and Alk is an alkylene group having from 1 to 4 carbon atoms.
L'invention concerne un procédé destiné à empêcher ou à minimiser la perte de teneur minérale des os chez les mammifères. Ce procédé consiste à administrer à un mammifère une quantité efficace d'un aminoalkylènephosphonate destinée à empêcher ou à minimiser la perte de teneur minérale des os. Les aminoalkylènephosphonates de la présente invention contiennent au moins un groupe R-N(Alk-PO¿3?H¿2?)¿2? ou au moins deux groupes RRïN-Alk-PO¿3?H¿2? dans lesquels R et R' peuvent être égaux ou différents, une fraction aliphatique ou cyclique, et Alk représente un groupe alcoylène possédant 1 à 4 atomes de carbone.
Dow Global Technologies Inc.
Smart & Biggar
The Dow Chemical Company
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