C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 271/10 (2006.01) A61K 31/42 (2006.01) A61K 31/45 (2006.01) C07C 229/34 (2006.01) C07C 309/24 (2006.01) C07C 311/51 (2006.01) C07D 233/84 (2006.01) C07D 249/04 (2006.01) C07D 249/12 (2006.01) C07D 257/04 (2006.01) C07D 257/06 (2006.01) C07D 261/06 (2006.01) C07D 285/12 (2006.01) C07F 9/09 (2006.01) C07F 9/38 (2006.01)
Patent
CA 2477423
The present invention encompasses compounds of Formula (I): as well as the pharmaceutically acceptable salts and hydrates thereof. The compounds are useful for treating immune mediated diseases and conditions, such as bone marrow, organ and tissue transplant rejection. Pharmaceutical compositions and methods of use are included.
L'invention concerne des composés représentés par la formule I, ainsi que des hydrates et des sels pharmaceutiquement acceptables de ces composés. Les composés sont utiles pour le traitement d'affections et de maladies immunitaires, telles que le rejet d'une transplantation de moelle osseuse, d'organe et de tissu. La présente invention concerne également des compositions pharmaceutiques et des méthodes d'utilisation de celles-ci.
Budhu Richard J.
Doherty George A.
Hale Jeffrey J.
Lynch Christopher L.
Mills Sander G.
Merck & Co. Inc.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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