Aminoalkylpyridineamides

C - Chemistry – Metallurgy – 07 – D

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C07D 213/40 (2006.01) A61K 31/44 (2006.01) C07D 213/63 (2006.01)

Patent

CA 1276025

ABSTRACT The compounds of this invention are aminoalkylpyridineamides represented by the formula Image wherein: R1 and R2 are the same or different members of the group consisting of halo, phenyl, substituted phenyl and a Image group wherein n, m and p are independently an integer of from 1 to 8 provided n + m + p is equal to or less than 10; x is thio, sulfinyl or sulfonyl; Alkl is straight or branched chain lower alkylene of 1 to 6 carbon atoms, R3 is lower alkyl, Alk2 is straight or branched chain alkylene of 1 to 4 carbon atoms; R4 is selected from the group consisting of hydrogen, halo, hydroxy, lower alkyl and lower alkoxy; and the pharmaceutically acceptable salts thereof. The compounds of the present invention are useful in the treatment of inflammation, allergy and hypersensitivity reactions and other disorders of the immune system.

500834

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