Aminoalkylthiodibenzthiepins and related compounds, a method...

C - Chemistry – Metallurgy – 07 – D

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260/246.9, 260/2

C07D 405/12 (2006.01) C07D 295/08 (2006.01) C07D 337/14 (2006.01)

Patent

CA 1110625

ABSTRACT OF THE DISCLOSURE The present application concerns novel amino- alkylthiodibenzthiepins of the formula I Image I wherein X is hydrogen, Y is hydrogen or halogen, and Z represent halogen or Image wherein R1 is hydrogen, lower alkyl, cyano, or phenoxycarbonyl and R2 is lower alkyl or R1-N-R2 forms a morpholino or a N-lower alkyl substituted piperazinyl; m is the integer 0 or 1; and n is an integer of from 2 to 4; and the physiologically tolerable acid addition salts thereof. The application is also directed to a method of preparing these compounds and pharmeuctical and veterinary preparations including them. The compounds are useful as antidepressants, analgetics and anticonvulsant agents.

317810

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