Aminobenzodiazepines

Details Aminobenzodiazepines Aminobenzodiazepines

C - Chemistry, Metallurgy

07

D

C07D 403/04 (2006.01) A61K 31/55 (2006.01)

Patent

CA 2044694

RAN 4430/43 Abstract Aminobenzodiazepines of formula Image I wherein R1 is H, NO2, halogen, CF3, lower alkyl, OH, lower alkoxy or CN, and R2 is H or CH3, and pharmaceutically acceptable salts thereof possess antiviral activity especially for the treatment or prophylaxis of viral infections, particularly ofretroviral infections, such as HIV 1 and/or HIV 2 infections, or for protecting cells against such infections. They can be prepared from corresponding benzodiazepinethiones.

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