Aminobenzoic acid derivatives

Details Aminobenzoic acid derivatives Aminobenzoic acid derivatives

C - Chemistry, Metallurgy

07

D

C07D 498/08 (2006.01) A61K 31/40 (2006.01) A61K 31/439 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) C07D 207/14 (2006.01) C07D 211/58 (2006.01) C07D 221/24 (2006.01) C07D 451/00 (2006.01) C07D 451/02 (2006.01) C07D 451/04 (2006.01) C07D 451/14 (2006.01) C07D 471/08 (2006.01) C07D 471/18 (2006.01) C07D 487/08 (2006.01) C07D 491/08 (2006.01)

Patent

CA 2128493

To provide a compound which exhibits a serotonin antagonism and an acetylcholine release accelerating activity at a well-balanced activity ratio. An aminobenzoic acid derivative represented by the general formula (I) or (II) or a pharmacologically acceptable salt thereof: (see formula I) (see formula II) [wherein R1 is selected from the group consisting of: (see formula III), (see formula IV), (see formula V) etc., (wherein A is a group represented by formula -CH2-X-CH2- (wherein X represents O, > N-R6 or > CHR7 (wherein R6 represents lower alkyl and R7 represents hydrogen or lower alkoxy)), etc.; D and E are each a group represented by formula -(CH2)3-, etc., and R2 represents lower alkyl, etc.}; R9 represents alkynyl; R10 represents amino, etc.; R11 represents halogen; R12 and R13 each represent lower alkyl; a is an integer of 1 to 5; and b is an integer of 0 to 5].

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