C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 235/14 (2006.01) A61K 31/4184 (2006.01) A61K 31/4427 (2006.01) A61K 31/454 (2006.01) A61K 31/4545 (2006.01) A61K 31/496 (2006.01) A61K 31/5377 (2006.01) C07D 401/08 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 403/08 (2006.01) C07D 405/08 (2006.01) C07D 405/10 (2006.01) C07D 405/14 (2006.01) C07D 409/08 (2006.01) C07D 409/14 (2006.01) C07D 413/08 (2006.01) C07D 413/14 (2006.01)
Patent
CA 2382322
The invention relates to aminocarbonyl-substituted benzimidazole derivatives of general formula (I) see above formula wherein the groups R1, R2, R3 and R4 may have the meanings given in the claims and in the specification, the prodrugs thereof, processes for preparing them and the use of benzimidazole derivatives as pharmaceutical compositions, particularly as pharmaceutical compositions with a tryptase-inhibiting activity.
La présente invention concerne des dérivés de benzimidazol substitués aminocabonyle de formule générale (I) dans laquelle les restes R<1>, R<2>, R<3> et R<4> peuvent correspondre aux éléments indiqués dans les revendications et la description, leurs promédicaments, leur procédé de préparation ainsi que l'utilisation de dérivés de benzimidazol comme produits pharmaceutiques, en particulier comme produit pharmaceutique à action inhibitrice sur la tryptase.
Anderskewitz Ralf
Braun Christine
Briem Hans
Disse Bernd
Hoenke Christoph
Boehringer Ingelheim Pharma Gmbh & Co. Kg
Boehringer Ingelheim Pharma Kg
Fetherstonhaugh & Co.
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