Aminocarboxylic acid complexes for the treatment of calcific...

Details Aminocarboxylic acid complexes for the treatment of calcific... Aminocarboxylic acid complexes for the treatment of calcific...

C - Chemistry, Metallurgy

07

F

167/101, 260/426

C07F 5/00 (2006.01) A61K 51/04 (2006.01)

Patent

CA 1270845

ABSTRACT OF THE DISCLOSURE Particle-emitting radionuclides, e.g. Samarium- -153, have been complexed with aminocarboxylic acid deri- vatives having at least one of the amine hydrogens replaced by a carboxyalkyl radical. The complexes have log of stability constant (Log K) from 13 to 20. Physiologically acceptable salts of these complexes are also contemplated by these complexes. These complexes are useful in the treatment of calcific tumors. These complexes have been found useful in the treatment of calcific tumors in animals. 33,173A-F

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