Aminocoumaran derivatives, their production and use

Details Aminocoumaran derivatives, their production and use Aminocoumaran derivatives, their production and use

C - Chemistry, Metallurgy

07

D

C07D 307/82 (2006.01) A61K 31/34 (2006.01) A61K 31/395 (2006.01) C07D 307/79 (2006.01) C07D 307/80 (2006.01) C07D 307/81 (2006.01) C07D 405/02 (2006.01) C07D 405/04 (2006.01) C07D 405/06 (2006.01) C07D 405/12 (2006.01) C07D 413/06 (2006.01) C07D 417/12 (2006.01) C07D 521/00 (2006.01)

Patent

CA 2054619

A novel aminocoumaran derivatives of the general formula (I): (see formula I) wherein R1 and R2 are a hydrogen atom, an aryl group, an alkoxycarbonyl group, an aliphatic group or aromatic group; R3, R4 and R5 are an optionally acylated hydroxyl, optionally substituted amino group, alkoxy group or aliphatic group, or two of R3, R4 and R5 may be linked together to form a carbocyclic group; R6 and R7 are an aliphatic group and at least one of them has a methylene group at the .alpha.-position; R8 and R9 are a hydrogen atom or an aliphatic group or aromatic group, or a salt thereof is useful for medicines for preventing and treating various diseases such as arterial schleosis, hepatopathy, cerebrovascular diseases and the like.

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