Aminocyclopentane alkenoic acids and esters and their...

Details Aminocyclopentane alkenoic acids and esters and their... Aminocyclopentane alkenoic acids and esters and their...

C - Chemistry, Metallurgy

07

D

260/247.1, 260/2

C07D 267/10 (2006.01) C07D 295/04 (2006.01)

Patent

CA 1173830

ABSTRACT Compounds are described of the formula Image (1) (and their salts and solvates) in which: X is cis or trans -CH=CH-; R1 is C1-7 alkyl terminated by -COOR3 where R3 is H, C1-6 alkyl or C7-10 aralkyl; Y is a saturated heterocyclic amino group having 5-8 ring members; and R2 is C2-4 alkanoyl, C3-6 alkenyl (optionally substituted), C1-12 alkyl, or substituted or unsubstituted phenylalkyl, biphenylalkyl or naphthylalkyl. These compounds inhibit blood platelet aggregation and bronchoconstriction and may be formulated for use as antithrombotic and anti-asthmatic agents.

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