Aminocyclopentane esters and their preparation and...

C - Chemistry – Metallurgy – 07 – D

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C07D 295/14 (2006.01) C07C 45/63 (2006.01) C07D 213/65 (2006.01) C07D 213/70 (2006.01) C07D 295/155 (2006.01) C07D 307/33 (2006.01) C07D 309/12 (2006.01) C07D 311/00 (2006.01) C07D 333/16 (2006.01) C07D 401/00 (2006.01) C07D 413/00 (2006.01)

Patent

CA 1190926

- 68 - ABSTRACT Compounds are described of the formulae Image in which -COR1 is a complex ester or thioester group, W is alkylene, X is cis or trans -CH=CH or -CH2CH2-, n is 1 or 2, Y is a saturated heterocyclic amino group having 5 - B ring members, and R2 is unsubstituted or substituted phenylalkyl, thienylalkyl, naphthylalkyl or cinnamyl, and their salts and solvates. These compounds inhabit blood platelet aggregation and bronchoconstriction and may be formulated for use as antithrombotic and antiasthmatic agents.

411565

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