A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
167/277, 260/600
A61K 31/135 (2006.01) A01N 41/10 (2006.01)
Patent
CA 1265534
ABSTRACT OF THE DISCLOSURE The invention relates to a new process for the preparation of aminodiaryl sulfoxide derivatives of the formula (I), Image (I) wherein X is halogen, alkoxy having from 1 to 6 carbon atoms or a group -(N,R,R1), in which R and R1 are hydrogen or alkyl having from 1 to 6 carbon atoms, R2 is hydrogen, halogen, alkyl or alkylthio having from 1 to 6 carbon atoms, alkoxy having from 1 to 6 carbon atoms or phenyl or phenylthio both optionally substituted by one or more identical or different halogen(s) and/or amino group(s), and acid addition salts thereof. The compounds of formula (I) are pharmaceutically active, in particular are potent anthelmintics, or can be used as active ingredients in pesticidal compositions. The invention therefore relates to pharmaceutical and pesticidal compositions containing compounds of formula (I) or salts thereof as active ingredient. - 2 - Compounds of formula (I), in which the substituents are as defined above, but if X stands for a group -N(R,R1) in which R and R1 both represent hydrogen, and X is in para-position related to the sulfoxide group, then R2 is other than hydrogen, halogen, alkyl having from 1 to 6 carbon atoms and alkoxy having from 1 to 6 carbon atoms, and the acid addition salts thereof, are new. These new compounds are also subject of the present invention.
475288
Csizer Eva
Deutsch Ida Nee Juhasz
Kreidl Janos
Meszaros Judit Nee Brill
Stefko Bela
Csizer Eva
Deutsch Ida Nee Juhasz
Fetherstonhaugh & Co.
Kreidl Janos
Meszaros Judit Nee Brill
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