Aminoethane sulfonamide orexin receptor antagonists

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 213/76 (2006.01) A61K 31/44 (2006.01) A61P 3/04 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2617324

The present invention is directed to aminoethane sulfonamide compounds which are antagonists of orexin receptors, and which are useful in the treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which orexin receptors are involved.

L'invention concerne des composés de sulfamide d'aminoéthane, lesquels sont antagonistes des récepteurs d'orexine. Ces composés sont utiles dans le traitement ou la prévention de troubles et maladies neurologiques et psychiatriques dans lesquels les récepteurs d'orexine sont impliqués. L'invention concerne également des compositions pharmaceutiques comprenant ces composés ainsi que l'utilisation de ces composés et compositions dans la prévention ou le traitement de telles maladies dans lesquelles les récepteurs d'orexine sont impliqués.

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