Aminoglycoside-aminocyclitol derivatives and process for...

C - Chemistry – Metallurgy – 12 – P

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C12P 19/44 (2006.01) C07H 15/224 (2006.01) C07H 15/232 (2006.01)

Patent

CA 1068226

ABSTRACT OF THE DISCLOSURE Novel aminoglycoside-aminocyclitol derivatives corresponding to the general formula : Image wherein R1 and R2, which are different, represent hydrogen or CH2NH2 and R is selected from the group consisting of : Image Image A = and B = wherein R3 represents NH2 or OH and R4 represents Image or Image wherein R5 represents hydrogen or methyl and the pharmaceutically acceptable acid addition salts thereof. They are useful as antibiotics.

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