Aminoglycoside derivatives processes for their production,...

C - Chemistry – Metallurgy – 07 – H

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260/230.52

C07H 15/20 (2006.01) C07H 15/224 (2006.01) C07H 15/234 (2006.01)

Patent

CA 1196629

AMINOGLYCOSIDE DERIVATIVES PROCESSES FOR THEIR PRODUCTION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND SUCH DERIVATIVES FOR USE AS PHARMACEUTICALS. Abstract Compounds of formula I, Image I wherein R1 represents hydrogen or a group of formula Image R2 represents hydroxy or amino, R3 represents hydrogen or hydroxy, R4 represents hydrogen or hydroxy, R5 represents amino, methylamino, dimathylamino or, when R2 represents amino, also hydroxy and R6 represents hydrogen or methyl, in free base form or in the form of an acid addition salt. These compounds can be used as chemotherapeuticals, in particular as anti-bacterially active antibiotics.

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