Aminoguanidine for treating niddm

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/155 (2006.01) A61K 31/00 (2006.01) A61K 31/175 (2006.01) A61K 31/44 (2006.01) A61K 31/655 (2006.01)

Patent

CA 2240492

A method for the treatment and/or prophylaxis of Type II diabetes, which method comprises the administration, to a human or non-human mammal, of an effective non-toxic pharmaceutically acceptable amount of an inhibitor of protein glycation, such as aminoguanidine. Preferably, the invention provides a method for the prophylactic treatment of Type II diabetes, in particular delaying or preventing the progression from hyperinsulinaemia to hyperglycaemia.

L'invention concerne un procédé pour le traitement et/ou la prophylaxie du diabète de type II, ledit procédé consistant à administrer à un mammifère humain ou non, une quantité efficace, non toxique et pharmaceutiquement acceptable, d'un inhibiteur de la glycosylation de protéines, tel que l'aminoguanidine. De préférence, l'invention concerne un procédé pour le traitement prophylactique du diabète de type II, en particulier pour retarder ou empêcher la progression de l'hyperinsulinémie vers l'hyperglycémie.

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