Aminoindane derivatives as serotonin and norepinephrine...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 317/58 (2006.01) A61K 31/135 (2006.01) A61K 31/357 (2006.01) A61K 31/36 (2006.01) A61P 25/22 (2006.01) A61P 25/24 (2006.01) C07C 211/42 (2006.01) C07D 317/48 (2006.01) C07D 319/18 (2006.01)

Patent

CA 2467337

The present invention relates to aminoindane derivatives having the formula I wherein X, Y, U, R1-2, R13-16 and R are as defined in the claims, or an acid addition salt thereof. The compounds of the invention posses the combined effect of serotonin reuptake inhibition and norepinephrine uptake inhibition.

La présente invention concerne des dérivés aminoindane représentés par la formule générale (I) dans laquelle X, Y, U, R?1-2¿, R?13-16¿ et R désignent des éléments définis dans les revendications de la présente demande, ou un de leurs sel d'addition acide. Les composés de l'invention permettent d'inhiber la recapture de la sérotonine et la capture de la norépinéphrine.

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